首页> 外国专利> COMPOSITIONS AND METHODS FOR TREATING NEUTROPENIA.

COMPOSITIONS AND METHODS FOR TREATING NEUTROPENIA.

机译:治疗中性粒细胞减少症的组合物和方法。

摘要

The invention relates methods of using a retinoid agonist and a G-CSF or an analog thereof to treat, prevent, reduce the likelihood of having, reduce the severity of and/or slow the progression of a condition in a subject. The retinoid agonist and the G-CSF or the analog thereof may be provided in a single composition or in separate compositions. A therapeutically effective amount of the retinoid agonist and the G-CSF or the analog thereof may be administered to the subject concurrently or sequentially. Conditions treatable with the methods and compositions include but are not limited to various forms of neutropenia and microbial infections. The invention also relates to methods for determining the efficacy of the treatments described herein.
机译:本发明涉及使用类维生素A激动剂和G-CSF或其类似物来治疗,预防,降低患有该病症,降低其严重性和/或减慢其进展的方法。类视黄醇激动剂和G-CSF或其类似物可以单一组合物或分开的组合物形式提供。治疗有效量的类维生素A激动剂和G-CSF或其类似物可以同时或顺序地施用于受试者。用所述方法和组合物可治疗的病症包括但不限于各种形式的中性粒细胞减少和微生物感染。本发明还涉及用于确定本文描述的治疗功效的方法。

著录项

  • 公开/公告号MX2016010699A

    专利类型

  • 公开/公告日2017-10-11

    原文格式PDF

  • 申请/专利权人 CHILDRENS HOSPITAL LOS ANGELES;

    申请/专利号MX20160010699

  • 发明设计人 LINGTAO WU;

    申请日2015-02-18

  • 分类号A61K31/203;A61K38/16;A61P31/04;C07K14/535;

  • 国家 MX

  • 入库时间 2022-08-21 13:37:46

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