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METHODS OF USING IL-1 ANTAGONISTS TO TREAT AUTOINFLAMMATORY DISEASE.
METHODS OF USING IL-1 ANTAGONISTS TO TREAT AUTOINFLAMMATORY DISEASE.
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机译:使用IL-1拮抗剂治疗自发性炎症的方法。
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摘要
Methods of treating, inhibiting, or ameliorating an autoinflammatory disorder, disease, or condition in a subject in need thereof, comprising administering to a subject in need a therapeutic amount of an interleukin 1 (IL-1) antagonist, wherein the autoinflammatory disorder, disease, or condition is treated, inhibited, or ameliorated. The IL-1 antagonist is a molecule capable of binding and inhibiting IL-1. The therapeutic methods are useful for treating a human adult or child suffering from Neonatal Onset Multisystem Inflammatory Disorder (NOM ID/CINCA), Muckle-Wells Syndrome (MWS), Familial Cold Autoinflammatory Syndrome (FCAS), familial mediterranean fever (FMF), tumor necrosis factor receptor-associated periodic fever syndrome (TRAPS), or systemic onset juvenile idiopathic arthritis (Still's Disease).
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机译:在有需要的受试者中治疗,抑制或改善自身炎性疾病,疾病或病状的方法,包括向有需要的受试者施用治疗量的白介素1(IL-1)拮抗剂,其中所述自身炎性疾病,或治疗,抑制或改善疾病。 IL-1拮抗剂是能够结合和抑制IL-1的分子。该治疗方法可用于治疗患有新生儿发作多系统炎性疾病(NOM ID / CINCA),Muckle-Wells综合征(MWS),家族性冷性自身炎综合征(FCAS),家族性地中海热(FMF),肿瘤的人类成人或儿童坏死因子受体相关的周期性发热综合征(TRAPS),或全身发作的幼年特发性关节炎(Still's Disease)。
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