Means and methods for spheroid cell culturing and analysis.

摘要

The invention relates to means and methods for cell culturing and cell analysis, in particular to devices designed for growth, maintenance and/or microscopic analysis of 3D cell culture models, like cell aggregates or spheroids. Provided is an insert plate for detachably attaching to a standardized microplate and having a plurality of wells, the insert plate having a main body comprising a plurality of tubes for receiving a sample, each tube having a liquid impermeable optically clear bottom portion to allow for microscopic imaging and wherein at least part of said bottom portion has a concave arcuate surface, the plurality of tubes being positioned to fit into and align with a corresponding well of the microplate when the microplate and the insert plate are attached. Also provided is an assembly of the insert plate and a microplate.