TRIFLURIDINE IN COMBINATION WITH TIPIRACIL OR A TIPIRACIL SALT, SUCH AS TIPIRACIL HYDROCHLORIDE

摘要

A cancer therapeutic drug enhanced efficacy and safety is provided. The cancer therapeutic drug, which is a composition containing ±,±,±-trifluorothymidine (FTD) and 5-chloro-6-(1-(2-iminopyrrolidinyl)methyl)uracil hydrochloride in a molar ratio of 1 : 0.5, and which is orally administered to a patient in need thereof at a dose, as a dose of FTD, of 20 to 80 mg/m 2 /day twice daily to four times daily.