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Chimeric Antigen receptor (CAR) comprising an Antigen binding domain, which binds selectively to the constant region of the TCR beta 1 (trbc1) or T Cell trbc2
Chimeric Antigen receptor (CAR) comprising an Antigen binding domain, which binds selectively to the constant region of the TCR beta 1 (trbc1) or T Cell trbc2
Refers to a Chimeric receptor (CAR) comprising an Antigen binding domain, which binds selectively to the constant region of the TCR beta 1 (trbc1 trbc2) or T Cell; the car that binds to trbc1 where the Antigen binding domain has a variable heavy chain (VH) that Comprises of SEQ ID no: CDR1, CDR2 7, SEQ ID no: 8CDr3 of SEQ ID no: 9 and a string variable Light (VL) which includes: CDR1 of SEQ ID no: 1, SEQ ID no: 11 of CDR2 and CDr3 of SEQ ID no: 12. It also refers to a method. The Invention is useful in the treatment of lymphoma or Leukemia T Cells
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机译：指包含抗原结合结构域的嵌合受体（CAR），该结构域选择性地与TCR beta 1（trbc1 trbc2）或T细胞的恒定区结合。与trbc1结合的汽车，其中抗原结合结构域具有可变重链（VH），该可变重链由SEQ ID no：CDR1，CDR2 7，SEQ ID no：8CDr3，SEQ ID no：9和字符串可变Light（VL）组成其包括：SEQ ID No：1的CDR1，CDR2的SEQ ID No：11和SEQ ID No：12的CDr3。本发明可用于治疗淋巴瘤或白血病T细胞
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