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Apocalypse inducers for cancer, immune and autoimmune diseases

机译:启示性癌症,免疫和自身免疫性疾病的诱导剂

摘要

a. A compound of formula A1 (n) or C (A2);A2, D1 and E1 are h, R1, or1, etc.; R1 is phenyl, heterogeneous, etc.; Y1 is h, CN, NO2, etc.; G1 is r1b, orb or nhr1b; r1b is s (o) 2 (O H),There are others The most popular compounds are: 3 - [(4 - [4 - [4 - [4 - [2 - (4 -) [4 - [2 - (4-chlorophenyl) - 4, 4-dimethoxyethane-1-en-1-il] methyl], pyridine-1-il-2 - (1H pirrorolo [2, 3-B] piridin-5-iloxi) benzyl alcohol], sulfuric acid - (2-nitrophenyl) amine] - 2 - [4 - [4 -] [4 -]4-chlorophenyl-4,4-dimethoxyethane-1-en-1-il-methyl) - 2 - (1H pirrozon [2,3-b] piridin-5-iloxi) benzoil} sulfonyl} - 2-nitrofenoxi) methyl] cyclohexane. He also mentioned a pharmaceutical composer These compounds inhibit the activity of Bcl-2 anti Apocalypse protein.If you are already registered, please log in first.
机译:一种。式A1(n)或C(A2)的化合物; A2,D1和E1为h,R1或or1等; R1是苯基,是非均相的;等等。 Y1是h,CN,NO2等; G1是r1b,orb或nhr1b; r1b是s(o)2(OH),还有其他最受欢迎的化合物是:3-[(4-[4-[4-[4-[2-(4-)] [4-[2-(4 -氯苯基)-4,4,4-二甲氧基乙烷-1-en-1-il]甲基],吡啶-1-il-2-(1H吡咯并[2,3-B] piridin-5-iloxi)苯甲醇],硫酸酸-(2-硝基苯基)胺]-2-[4-[4-] [4-] 4-氯苯基-4,4-二甲氧基乙烷-1-en-1-il-甲基)-2-(1H吡咯啉[ 2,3-b]吡啶--5-碘)苯甲酰基}磺酰基} -2-硝基苯氧基)甲基]环己烷。他还提到了药物作曲家。这些化合物抑制Bcl-2抗启示蛋白的活性。如果您已经注册,请先登录。

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