Composition for the prolonged releasing of heparin and the application of the alginate hydroxypropyl cellulose gel for the prolonged releasing of heparin

摘要

The composition for the prolonged release of heparin, wherein the gel obtained from the alkali metal alginate and hydroxypropylcellulose at the weight ratio from 2:1 to 5:1 is used subjected to the gelling process using calcium salt, containing immobilised heparin in the amount from 0.01 to 10% w/w. The invention also relates to the use of the gel obtained from sodium alginate and hydroxypropylcellulose for the prolonged release of heparin.