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Crystalline form of the complex of (2-amino-5-guanidine-pentane)di(thiocyanate)copper(II) and method for producing it

机译:[(2-氨基-5-胍-戊烷)二(硫氰酸酯)铜(II)]配合物的晶体形式及其制备方法

摘要

the invention relates to crystalline forms of the complex [(2 - amino - 5 - guanidynopentano) di (tiocyjaniano)] copper (ii) of formula 1 applicable as a constituent of preparations against bacterial infections.the invention discloses a crystalline form of complex manufacturing and [(2 - amino - 5 - guanidynopentano) di (tiocyjaniano)] copper (ii) with formula 1, which is characterized by the fact that aqueous salt selected from copper (ii) salt or salt sulphate (vi) copper (ii)soluble in water and subjected to the reaction with two parts molowymi acid solution 2 - amino - 5 - guanidynopentanowego and two parts molowymi salt solution of potassium thiocyanate with reactions leads using a magnetic stirrer, with continuous stirring,then after a minimum 72 hours is a crystalline form of the complex [(2 - amino - 5 - guanidynopentano) di (tiocyjaniano)] copper (ii) of formula 1.
机译:本发明涉及式(1)的配合物[(2-氨基-5-胍基戊五烷)二(噻吩并亚诺亚诺)]铜(ii)的晶型,其可用作抗细菌感染的制剂的成分。本发明公开了复合物制造的晶型。以及具有式1的[(2-氨基-5-胍基戊烷)二(噻唑亚诺)]铜(ii),其特征在于选自铜(ii)盐或硫酸盐(vi)铜(ii)的水盐易溶于水并与两部分的Molowymi酸溶液2-氨基-5-胍基戊戊磺酸钠和两部分的Molowymi盐溶液与硫氰酸钾反应,并用磁力搅拌器进行反应,连续搅拌,然后至少72小时后式1的配合物[((2--氨基-5-胍基戊戊)二(噻唑亚诺))]的结晶形式。

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