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EXTRACELLULAR VESICLES DERIVED FROM GRAM-POSITIVE BACTERIA, AND USE THEREOF

机译:革兰氏阳性细菌衍生的细胞外囊泡及其使用

摘要

The present invention relates to extracellular vesicles (EVs) derived from gram-positive bacteria. In detail, the present invention provides animal models of disease using extracellular vesicles derived from gram-positive bacteria, provides a method for screening an active candidate substance which is capable of preventing or treating diseases through the animal models of disease, provides vaccines for preventing or treating diseases caused by extracellular vesicles derived from gram-positive bacteria, and provides a method for diagnosing the causative factors of diseases caused by gram-positive bacteria using extracellular vesicles.
机译:本发明涉及衍生自革兰氏阳性细菌的细胞外囊泡(EVs)。详细地,本发明提供了使用衍生自革兰氏阳性细菌的细胞外囊泡的疾病的动物模型,提供了通过疾病的动物模型筛选能够预防或治疗疾病的活性候选物质的方法,提供了用于预防或预防疾病的疫苗。治疗由革兰氏阳性细菌引起的细胞外囊泡引起的疾病,并提供了一种利用细胞外囊泡诊断由革兰氏阳性细菌引起的疾病的病因的方法。

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