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PROCESS FOR THE PREPARATION OF PEMETREXED AND LYSIN SALT THEREOF
PROCESS FOR THE PREPARATION OF PEMETREXED AND LYSIN SALT THEREOF
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机译:制备佩特美和赖氨酸盐的方法
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摘要
The present invention refers to a process for the synthesis of pemetrexed and salts thereof, in particular to a lysine salt thereof, to said salt as such and to pharmaceutical compositions that comprise the same. Furthermore, the present disclosure also relates to a crystalline form of the synthesis intermediate pemetrexed diethyl ether and a crystalline form of the pemetrexed lysine salt.
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