inhibition of the generation of ros in hypoxia dependent decrease the resistance to anticancer drugs, and formation of cancer stem cells radioresistenza and metastatic phenotype

摘要

The present invention relates to the use of systems involved in ROS generation (reactive oxygen species) to reduce resistance to chemotherapy and radiation therapy, reduce cancer stem cell formation and inhibit the metastatic phenotype; the subject matter of the invention further relates to inhibitors of ROS generation serving to reduce resistance to chemotherapy and radiation therapy and inhibit cancer stem cell formation and inhibit the metastatic phenotype.