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Compound intended for oral absorption of nicotine with the aim of quitting smoking

机译:用于口服吸收尼古丁以戒烟的化合物

摘要

The compound intended for the oral application of nicotine to the circulatory system and distribution to the central nervous system, applicable in colloidal form or in the form of an atomizing device in order to quit smoking or its replacement in the case of being the conditions for Unfavorable smoking In accordance with the invention in reference, the compound stands out for the fact that it contains a solution of nicotine in the form of a base and / or its salts with an organic acid in a concentration of 0.10 to 4.00% of the weight, the most appropriate concentration is 0.20 to 1.00% of the weight. It also contains materials that have a mucolytic effect of the acetylcysteine group in a concentration of 3.00 to 30.0% of the weight and / or phytocomplexes that have a mucolytic effect, acquired by extracting the selected plants from the Primula veris, Primula elatior group Hedera helix, Eucalyptus globulus nebo Liquiritia glabra in a concentration of 0.50 to 15.00% of the phytocomplex weight with an antioxidant effect selected from the group of flavones, flavonols, flavanones flavanones, isoflavones, neoflavonoids, anthocyanidins, pro-anthocyanins and their oligomers and polymers, acquired by extracting Camellia sinensis, Curcuma longa, Rosmarinus officinalis, Sylibium marianum, Vitis vinifera, Ginkgo biloba, Euterpe oleracea, Vaccinium myrtillus, Morinda citrifolia, Malpighia glabra plants, which also contain a retarder (buffer) which modifies acidity at a pH range of 7.0 to 9.0.
机译:用于口服尼古丁到循环系统并分配到中枢神经系统的化合物,可以胶体形式或以雾化装置形式使用,以在不适宜的情况下戒烟或替代烟碱吸烟根据本发明,该化合物突出的事实是,它含有碱和/或其盐与有机酸的盐形式的尼古丁溶液,其浓度为重量的0.10至4.00%,最合适的浓度是重量的0.20至1.00%。它还包含浓度为重量的3.00%至30.0%的乙酰半胱氨酸基团具有粘液溶解作用的物质和/或具有粘液溶解作用的植物复合物,这些物质是通过从报春花中提取的精选植物从报春花中提取的。 ,浓度为植物复合物重量的0.50至15.00%的中性桉树,具有抗氧化作用,其选自黄酮,黄酮醇,黄烷酮,黄烷酮,异黄酮,新黄酮,花色素苷,原花色素及其低聚物和通过提取山茶,姜黄,迷迭香,马齿兰,葡萄,葡萄,银杏,欧洲菊,巴戟天,马来草等植物,这些植物也含有在pH7.0下调节酸度的阻滞剂(缓冲液)到9.0。

著录项

  • 公开/公告号ES2606546T3

    专利类型

  • 公开/公告日2017-03-24

    原文格式PDF

  • 申请/专利权人 HEGLUND A.S.;

    申请/专利号ES20100721627T

  • 发明设计人 KOSIK DOBROMIL;DITTRICH MILAN;

    申请日2010-02-03

  • 分类号A61K9/08;A61K31/465;A61K36;

  • 国家 ES

  • 入库时间 2022-08-21 13:35:24

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