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Synthesis procedures of factor Xa inhibitors
Synthesis procedures of factor Xa inhibitors
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机译:Xa因子抑制剂的合成程序
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摘要
A method of preparing a compound of Formula II, or a salt thereof: ** Formula ** comprising contacting a compound of Formula II-A: ** Formula ** with a compound of Formula II-B: * * Formula ** under reaction conditions, forming the compound of Formula II or the salt thereof; where R1 and R2 are independently C1-6 alkyl; R3 and R4 are independently selected from the group consisting of hydrogen, fluoro, chloro, bromo and methoxy; and R5 is selected from the group consisting of fluoro, chloro, bromo and methoxy.
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