Formulation low bioavailability substances, containing a salt of N-acetylcysteine-chitosan

摘要

A composition comprising: a) a core comprising at least one active principle with low bioavailability, a polysorbate and a salt of chitosan-N-acetylcysteine; b) an enteric coating layer enclosing said core a), wherein said salt of N-acetylcysteine ​​chitosan comprised in a) is obtained by protonation of the free amino group of chitosan by N-acetylcysteine, behaving as an acid .