Use of genetically modified mesenchymal stem cells to express a suicide gene to treat cancer

摘要

Use of a mesenchymal stem cell that expresses a suicide gene for the manufacture of a medicine to treat cancer, in which the suicide gene is a gene that codes for cytosine deaminase, in which the cytosine deaminase of the suicide gene converts 5 -fluorocytosine in 5-fluorouracil, in which the mesenchymal stem cell is a human mesenchymal stem cell isolated from bone marrow, peripheral blood or blood from the umbilical cord, and in which cancer is selected from brain cancer, breast cancer, cancer liver, pancreatic cancer, colorectal cancer and lung cancer.