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automated analyzer for clinical laboratory

机译:临床实验室自动化分析仪

摘要

A laboratory automation system (10) that is adapted to carry out clinical chemistry and immunoassay tests, wherein the system comprises: - microwell plates (P) as reaction vessels, - one or more immunoassay processors ( 140, 140a), designed as a magnetic particle processor, located in a first secondary section (66) of an analysis section (60) of the system, wherein the magnetic particle processor includes magnetic rods (162) that are covered with the tips or wraps of combs of disposable tips (164) to move magnetic particles from one microwell to another microwell, where the magnetic particle processor includes magnetic rods (162) that are adapted to move magnetic particles from one microwell to another microwell when covered with the tips or wraps of the disposable tip combs (164), - one or more test processors of clinical chemistry (142) located in a second secondary section (68), different from the first secondary section, of the system analysis section, and - the same aspiration / dosing device (94) for aspirating and dosing liquids for both immunoassays as for clinical chemistry tests, - storage shelves (144) for the microwell plates that are located in or near the second secondary section of the analysis section, - a stack units (146) for the microwell plates for storing the microwell plates for immunoassays and clinical chemistry assays prior to the kit preparation of the microwell plates for immunoassays or clinical chemistry assays, and - an absorbance reader that is integrated into the clinical chemistry assay processor located in the second secondary section of the analysis section to read the clinical chemistry test results from the pl Microwells after processing the reaction mixture, - containers (128) for solid waste and shelves (126) for disposable pipette tips that are located at or near the center of the analysis section (60), - a third secondary section (62) of the analysis section (60) comprising containers for retaining samples and reagents to be used in the tests, cuvettes (116a, 116b, 116c) for containing bulk liquids, such that the Pipette tips (110) can simultaneously aspirate a liquid, - a fourth secondary section (64) of the analysis section (60) comprising a storage area (120) for pipette tips and a plate rotation unit of temperature controllable microwells (122) or stationary suction / dosing locations (124), and shelves (130) for tip combs (164), shelves (132) for used tip combs (164), about shelves (134) pa ra pipette tips, and a shelf stacking unit (136) for disposable tips, - a luminescence reader (150) separated from the immunoassay processor located in the first secondary section (66) of the analysis section to read the results of the immunoassay from the microwell plates after the reaction mixtures have been processed, - an endless belt conveyor (151) to move the microwell plates from the magnetic particle processor to the luminescence reader (150), in where the one or more immunoassay processors are adapted to provide the following functions: incubation of reaction mixtures, mixing of reaction mixtures, separation of components of reaction mixtures, washing of the product or reaction products, and release of a label for enable the reading of immunoassay results, and where the one or more clinical chemistry trial processors are ad suitable for providing the following functions: incubation of reaction mixtures, mixing of reaction mixtures, carrying out a reading with a blank sample, carrying out a reading of a reaction mixture.
机译:一种适于执行临床化学和免疫分析测试的实验室自动化系统(10),其中该系统包括:-作为反应容器的微孔板(P),-设计为磁性的一个或多个免疫分析处理器(140、140a)粒子处理器,位于系统的分析部分(60)的第一个次级部分(66)中,其中磁性粒子处理器包括磁棒(162),磁棒(162)覆盖着尖端或一次性尖端的梳状包裹物(164)将磁性颗粒从一个微孔移动到另一个微孔的方法,其中磁性颗粒处理器包括磁棒(162),当覆盖有一次性尖端梳子(164)的尖端或包裹物时,该磁棒适于将磁性颗粒从一个微孔移动到另一个微孔,-位于系统分析部分第二次级部分(68)中的一个或多个临床化学测试处理器(142),不同于第二次级部分(68)--相同的吸取量/ d用于为两种免疫测定抽吸和定量液体的取样装置(94),用于临床化学测试;-位于分析部分第二个次级部分或附近的微孔板的存储架(144);-堆叠单元(146) )用于在准备用于免疫测定或临床化学测定的微孔板试剂盒之前准备用于存储用于免疫测定和临床化学测定的微孔板的微孔板,以及-集成在第二个中的临床化学测定处理器中的吸光度读取器分析部分的第二部分,用于在处理反应混合物后读取pl微孔的临床化学测试结果,-位于固体中心或附近的用于固体废物的容器(128)和用于一次性移液器吸头的架子(126)。分析部分(60),-分析部分(60)的第三次要部分(62),其包括用于容纳待测样品和试剂的容器在测试中使用的比色皿(116a,116b,116c)用于盛装散装液体,以使移液器吸头(110)可以同时吸出液体,-分析部分(60)的第四次要部分(64),包括储存器区域(120)(用于移液器吸头)和温度可控的微孔(122)或固定抽吸/定量位置(124)的板旋转单元,以及用于尖端梳(164)的架子(130),用于旧式尖端梳的架子(132)( 164),关于移液管吸头的架子(134)和用于一次性吸头的架子堆叠单元(136),-与位于分析部分的第一次级部分(66)中的免疫测定处理器分开的发光阅读器(150)在处理反应混合物后从微孔板读取免疫测定的结果,-环形带式输送机(151),将微孔板从磁性颗粒处理器移至发光读取器(150),其中更多的免疫测定仪适用于p提供以下功能:反应混合物的温育,反应混合物的混合,反应混合物的成分分离,产物或反应产物的洗涤以及释放标记以读取免疫测定结果以及一种或多种临床方法化学试验处理器适合提供以下功能:反应混合物的温育,反应混合物的混合,用空白样品进行读数,对反应混合物进行读数。

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