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ANTAGONIST IL-7 RECEPTOR ANTIBODIES TO TREAT TYPE 2 DIABETES AND IMMUNOLOGICAL DISORDERS
ANTAGONIST IL-7 RECEPTOR ANTIBODIES TO TREAT TYPE 2 DIABETES AND IMMUNOLOGICAL DISORDERS
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机译:治疗2型糖尿病和免疫性疾病的拮抗剂IL-7受体抗体
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摘要
The present invention provides antagonizing antibodies that bind to interleukin-7 receptor (IL-7R). The invention further provides a method of obtaining such antibodies and antibody-encoding nucleic acids. The invention further relates to therapeutic methods for use of these antibodies and antigen-binding portions thereof for the treatment and/or prevention of type 2 diabetes and immunological disorders, including type 1 diabetes, multiple sclerosis, rheumatoid arthritis, graft-versus-host disease, and lupus.
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