A computer-implemented method for alternating malware classifiers in an attempt to frustrate brute-force malware testing may include (1) providing a group of heuristic-based classifiers for detecting malware, wherein each classifier within the group differs from all other classifiers within the group but has an accuracy rate that is substantially similar to all other classifiers within the group, (2) including the group of classifiers within a security-software product, and (3) alternating the security-software product's use of the classifiers within the group in an attempt to frustrate brute-force malware testing by (a) randomly selecting and activating an initial classifier from within the group and then, upon completion of a select interval, (b) replacing the initial classifier with an additional classifier randomly selected from within the group. Various other methods, systems, and computer-readable media are also disclosed.
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