ORALLY FAST DISSOLVING FILM FORMULATION INCLUDING ARIPIPRAZOLE AND METHOD FOR PRODUCING THE SAME

摘要

The present invention relates to an orally fast dissolving film formulation including aripiprazole. Specifically, the orally fast dissolving film formulation includes aripiprazole or a pharmaceutically acceptable salt thereof that is substantially free of amorphous particles. The orally fast dissolving film formulation is comparable to an original aripiprazole tablet in terms of both dissolution and uptake rate, ensuring high dissolution rate of aripiprazole without any risk of damage to oral tissues. In addition, the orally fast dissolving film formulation is effective in masking a bitter taste of aripiprazole, achieving superior medication compliance. The present invention also relates to a method for producing the orally fast dissolving film formulation.