首页> 外国专利> A method of treating solid cancers and/or metastases thereof, medicaments therefore, and a method of predicting the clinical outcome of treating solid cancers and/or metastases thereof

A method of treating solid cancers and/or metastases thereof, medicaments therefore, and a method of predicting the clinical outcome of treating solid cancers and/or metastases thereof

机译:治疗实体癌和/或其转移的方法,因此的药物以及预测治疗实体癌和/或其转移的临床结果的方法

摘要

The instant invention provides for a new method of treating colorectal cancer (CRC) and metastases thereof in subjects, and preferably also of other solid cancers and metastases thereof in subjects, wherein said method preferably depends on whether the patient shows certain specific proteins levels in one or more body fluids prior to or during treatment, wherein said treatment comprises the administration of at least one pan αv integrin inhibitor to a patient, a medicament for use in said new methods, and a method of predicting the outcome of a treatment with at least one pan αv integrin inhibitor based on said specific protein levels in one or more body fluids of the patient.
机译:本发明提供了一种治疗受试者的结肠直肠癌(CRC)及其转移的新方法,并且优选地还治疗受试者的其他实体癌及其转移的新方法,其中所述方法优选地取决于患者是否在一个人中显示某些特定的蛋白质水平。治疗前或治疗期间的一种或多种体液,其中所述治疗包括向患者施用至少一种泛αv整联蛋白抑制剂,用于所述新方法的药物以及通过至少一种方法预测治疗结果的方法基于患者一种或多种体液中的特定蛋白质水平的一种泛αv整联蛋白抑制剂。

著录项

  • 公开/公告号AU2015317409A1

    专利类型

  • 公开/公告日2017-04-27

    原文格式PDF

  • 申请/专利权人 MERCK PATENT GMBH;

    申请/专利号AU20150317409

  • 发明设计人 STRAUB JOSEF;STAUB EIKE;

    申请日2015-08-18

  • 分类号A61K39/395;G01N33/574;

  • 国家 AU

  • 入库时间 2022-08-21 13:32:47

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