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Composition for use in increasing engraftment efficacy of haematopoetic stem cells after transplantation
Composition for use in increasing engraftment efficacy of haematopoetic stem cells after transplantation
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机译:用于提高移植后造血干细胞的移植效力的组合物
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摘要
The present invention provides the new use of composition comprising at least one inhibitor of dipeptidyl peptidase IV (DPP-IV) for increasing migration and homing of haematopoetic progenitor cells in stem cell transplanted recipients, wherein said haematopoetic stem and/or progenitor cells had been treated in vitro with an engraftment enhancing compound, specifically with a prostacyclin analogue and a cAMP enhancer before transplantation.
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