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CELL EVALUATION METHOD, HIGH-PERFORMANCE CELL OR DRUG SCREENING METHOD, AND PHARMACEUTICAL COMPOSITION

机译:细胞评估方法,高效能细胞或药物筛查方法以及药物成分

摘要

The present invention addresses the problem of providing: a method for evaluating whether cells are effective in the treatment of diseases, and the like, associated with intracellular mitochondrial dysfunction and a reduction in mitochondrial activity, and in the amelioration of symptoms associated with aging and the like; high-performance cells judged to be effective by this method; and a method for obtaining a drug capable of inducing such high-performance cells. The present invention is a cell evaluation method for evaluating a cell using, as the indicator, the capability of mitochondrial transference to other cells. Further, mitochondrial activity is preferred as the indicator. The mitochondrial activity is at least one selected from the group consisting of mitochondrial dehydrogenase activity, mitochondrial content, and mitochondrial membrane potential.
机译:本发明解决了提供以下问题:提供一种方法,用于评估细胞是否有效治疗与细胞内线粒体功能障碍和线粒体活性降低有关的疾病等,并改善与衰老相关的症状。喜欢;通过这种方法判断为有效的高性能细胞;获得能够诱导这种高性能细胞的药物的方法。本发明是以细胞线粒体向其他细胞的转移能力为指标的细胞评价方法。此外,线粒体活性优选作为指示剂。线粒体活性是选自由线粒体脱氢酶活性,线粒体含量和线粒体膜电位组成的组中的至少一种。

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