Immunotherapeutic targeting of placental-like chondroitin sulfate using chimeric antigen receptors (CARs) and immunotherapeutic targeting of cancer using CARs with split-protein binding systems

摘要

The present invention relates to polypeptides comprising conditionally active chimeric antigen receptor (CAR) and a split-protein binding system, a VAR2CSA polypeptide, or any other targeting agent. The present invention further relates to polypeptides comprising VAR2CSA polypeptides or other targeting agent, and a split-protein binding system.