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METHOD FOR DIAGNOSING HEPATIC FIBROSIS BASED ON BACTERIAL PROFILE AND DIVERSITY

机译:细菌外形和多样性的肝纤维化诊断方法

摘要

The present invention concerns methods for diagnosing liver fibrosis in an obese subject, said method comprising the steps of a) determining bacterial diversity in a biological sample from the subject, and b) based on the result of the bacterial diversity determination in step a), diagnosing liver fibrosis in the subject, or comprising the steps of a1) determining the proportion of bacteria belonging to a particular taxon and the proportion of bacteria belonging to at least one other particular taxon, in a biological sample of said subject, a2) combining the proportions determined in step a1) to obtain a combination value, and b) based on the combination value obtained in step a2), diagnosing liver fibrosis in the subject.
机译:本发明涉及用于诊断肥胖受试者的肝纤维化的方法,所述方法包括以下步骤:a)确定来自受试者的生物样品中细菌的多样性,以及b)基于步骤a)中细菌多样性确定的结果,诊断所述受试者的肝纤维化,或包括以下步骤:a1)在所述受试者的生物样品中确定属于特定分类群的细菌的比例和属于至少一种其他特定分类群的细菌的比例,a2)将所述在步骤a1)中确定的比例以获得组合值,以及b)根据在步骤a2)中获得的组合值,诊断对象的肝纤维化。

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