A DIRECT SCREW-DRIVEN CELL/BIOLOGICS FABRICATION HEAD FOR THE ASSEMBLY OF 3D TISSUE CONSTRUCTS

摘要

Tissue generation have advanced tremendously in recent decades. Precision motion systems present a unique opportunity to establish new platforms to fabrication living tissue constructs. The key of successfully building a functional tissue construct, is having the right tool. In order to assemble cells into a functional array, the fabrication head must sustain cell life and have full control of the fluid/bio-suspension being printed. This article presents a direct screw-driven cell/biologics deposition fabrication head for the assembly of three-dimensional tissue constructs. This fabrication head is designed to be 100% biocompatible, sustain cell life, and has full control of mass flow rate with interchangeable nozzles.