ELECTRON, RADICAL, OR REACTIVE OXYGEN SPECIES-SCAVENGING AGENT BASED THERAPY OF INBORN ERRORS OF FATTY ACID OXIDATION AND OXIDATIVE PHOSPHORYLATION

摘要

A method is provided for treating a fatty acid oxidation metabolic condition, such as an inborn error of fatty acid oxidation or oxidative phosphorylation, and/or hypoglycemia, rhabdomyolysis, or cardiomyopathy in a patient. A mitochondrial-targeted electron, radical, or ROS-scavenging agent is administered to the patient in an amount effective to treat, mitigate or prevent any fatty acid oxidation metabolic condition, such as inborn errors of fatty acid oxidation or oxidative phosphorylation, and/or hypoglycemia, rhabdomyolysis, or cardiomyopathy in a patient.