1256- PROCESS FOR THE ISOLATION OF 1256-HEXANETETROL FROM SORBITOL HYDROGENOLYSIS REACTION MIXTURES USING SIMULATED MOVING BED CHROMOTOGRAPHY

摘要

1,2,5,6-hexanetetrol (HTO), and other by-products of the hydrogenation reaction of sugar alcohols and / or mono- or di-dehydrated products of sugar alcohols, A method of isolating and purifying 6-hexanetetrol (HTO) is described. The method comprises the steps of contacting a mixture comprising HTO and other C ₁ -C ₆ alcohols and a polyol with a resin material adapted for chromatography under conditions such that HTO preferentially binds to the resin relative to other components in the mixture, And eluting HTO from the resin using a solvent.