NMDAR COMBINATIONS OF NMDAR MODULATING COMPOUNDS

摘要

The present disclosure features combinations of NMDAR modulating compounds. The present disclosure features a combination comprising one or more NMDAR antagonists and GLYX-13 (each of which is referred to herein as an "ingredient"). The beneficial effect of the combination is that the administration of GLYX-13 (e. G., A single dose) is sufficient to induce NMDAR antagonist-induced cognitive dysfunction (e. G., NMDAR antagonist-induced dysfunction in new object recognition, Lt; RTI ID = 0.0 and / or / RTI induced by repeated dosing).