PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NON-ALCOHOLIC FATTY LIVER DISEASE COMPRISING QUERCETIN-3-O-GLUCOSIDE

摘要

The present invention relates to a pharmaceutical composition comprising quercetin-3-O-glucoside for preventing or treating a non-alcoholic fatty liver disease (NAFLD). The composition comprising quercetin-3-O-glucoside as an active ingredient according to the present invention causes no side-effects, such as cardiovascular action, central action, liver disorder and kidney disorder, caused by the conventional synthetic pharmaceutical compositions. In addition, the composition according to the present invention reduces the body weight causing a non-alcoholic fatty liver disease, inhibits growth of non-alcoholic fatty liver, and effectively reduces total cholesterols, LDL-cholesterols or triglycerides. Further, the composition can effectively inhibit the activities of SREBP-1c, MGAT1 and PPAR-γ, and thus is useful for a pharmaceutical composition for preventing and/or treating a non-alcoholic fatty liver disease, and/or a health-aid food composition for preventing and/or improving a non-alcoholic fatty liver disease.;COPYRIGHT KIPO 2017