COPD TRPM8- 2--4--13- 2-ARYL-4-HYDROXY-13-THIAZOLE DERIVATIVES USEFUL AS TRPM8-INHIBITORS IN TREATMENT OF NEURALGIA PAIN COPD AND ASTHMA

摘要

The present invention relates to a compound which acts as a selective antagonist of the transient receptor potential cation channel subfamily M member 8 (hereinafter referred to as TRPM8) having the formula (I) , Ischemia, neurodegeneration, stroke, mental disorders, itching, irritable bowel disease, cold-induced and / or aggravated respiratory disorders, and urological disorders: (I) .