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ADSORBENT FOR ORAL ADMINISTRATION THERAPEUTIC AGENT FOR RENAL DISEASES AND THERAPEUTIC AGENT FOR HEPATIC DISEASES

机译:口服给药治疗肾病的药物和肝病治疗的药物

摘要

An object of the present invention is to provide an adsorbent for oral administration capable of adsorbing a large amount of indole in the presence of bile acid. The above problem is solved by a process for producing a polyurethane foam having a specific surface area of 800 m 2 / g or more, a bulk density of 0.3 to 0.8 g / mL, a pore volume of less than 3 nm, (1): Vm = Vmic / Vmet (1) wherein Vmic is a pore volume of less than 3 nm in diameter and Vmet is a pore volume of 3 to 50 nm in pore diameter, And a spherical activated carbon having a porosity ratio (Vm) of not less than 3.0 can be solved by an adsorbent for oral administration.
机译:本发明的目的是提供一种口服给药的吸附剂,其在胆汁酸存在下能够吸附大量的吲哚。通过生产比表面积为800m 2 / g或更大,堆积密度为0.3-0.8g / mL,孔体积较小的聚氨酯泡沫的方法解决了上述问题。小于3nm,(1):Vm = Vmic / Vmet(1)其中,Vmic是直径小于3nm的孔体积,Vmet是孔径为3-50nm的孔体积,以及具有通过口服用吸附剂可以解决孔隙率(Vm)不小于3.0。

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