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CpG METHOD FOR CONTROLLING DIFFERENTIATIN OF STEM CELL BY EPIGENETIC MODIFICATION OF INTRAGENIC CPG ISLAND

机译:CpG方法通过内源性CPG岛的表观修饰来控制干细胞的分化

摘要

The present invention relates to a method for regulating differentiation of stem cells through epigenetic modification of CpG island (intragenic CGI) in genetic structures. More specifically, the present invention relates tot a method for regulating differentiation of stem cells through regulation of DNA methylation on CGI in genetic structures, method for detecting differentiation ability of stem cells, a method for screening drugs for regulating differentiation of stem cells, and a kit for detecting differentiation of stem cells.
机译:本发明涉及通过遗传结构中的CpG岛(基因内CGI)的表观遗传修饰来调节干细胞分化的方法。更具体地,本发明涉及通过调节遗传结构中CGI上的DNA甲基化来调节干细胞分化的方法,检测干细胞分化能力的方法,筛选用于调节干细胞分化的药物的方法,以及用于检测干细胞分化的试剂盒。

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