首页> 外国专利> RECOMBINANT MICROORGANISM FOR PRODUCING 1,3-PROPANEDIOL WITHOUT ABILITY OF PRODUCING 2,3-BUTANEDIOL

RECOMBINANT MICROORGANISM FOR PRODUCING 1,3-PROPANEDIOL WITHOUT ABILITY OF PRODUCING 2,3-BUTANEDIOL

机译:不能生产2,3-丁二醇的重组微生物生产1,3-丙二醇

摘要

The present invention relates to a recombinant microorganism with an ability of producing 1,3-propanediol. In the microorganism with an ability of producing 1,3-propanediol, a gene for coding glycosyltransferases involved in biosynthesis of lipopolysaccharides, a gene for coding lactate dehydrogenase and a gene for coding α-acetolactate decarboxylase are deleted, and dhaT operon and formate dehydrogenase are overexpressed. According to the present invention, 1,3-propanediol can be industrially versatile in a polymer monomer, medical industries, industry resin, etc. can be produced with high efficiency from glycerol without 2,3-butanediol which is a by-product.;COPYRIGHT KIPO 2017
机译:本发明涉及具有生产1,3-丙二醇的能力的重组微生物。在具有产生1,3-丙二醇能力的微生物中,缺失了用于参与脂多糖的生物合成的编码糖基转移酶的基因,编码乳酸脱氢酶的基因和编码α-乙酰乳酸脱羧酶的基因,并且去除了dhaT操纵子和甲酸酯脱氢酶。过度表达。根据本发明,在没有单体副产物2,3-丁二醇的情况下,由甘油可以高效地生产1,3-丙二醇在聚合物单体中的工业用途,医药工业,工业树脂等。版权KIPO 2017

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