首页> 外国专利> ORAL PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF IMMUNE DISEASE AND METABOLIC DISEASE COMPRISING REBAMIPIDE PRODRUG

ORAL PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF IMMUNE DISEASE AND METABOLIC DISEASE COMPRISING REBAMIPIDE PRODRUG

机译:预防或治疗包含瑞巴肽的免疫疾病和代谢性疾病的口服药物组合物

摘要

The present invention relates to an orally administered pharmaceutical composition comprising a rebamipide precursor for preventing or treating immune diseases and metabolic diseases. Specifically, the present invention relates to an orally administered pharmaceutical composition capable of preventing or treating immune diseases such as rheumatoid arthritis and osteoarthritis, and metabolic diseases such as obesity, hyperlipidemia, diabetes, diabetic complications, irritable bowel syndrome, gastric ulcer, and gastritis, by comprising a rebamipide precursor or a pharmaceutically acceptable salt thereof as an active ingredient. The orally administered pharmaceutical composition according to the present invention, by comprising a rebamipide precursor or a pharmaceutically acceptable salt thereof as an active ingredient, can have the treatment effects comparable or superior to that of rebamipide for immune diseases such as rheumatoid arthritis and osteoarthritis, and metabolic diseases such as obesity, hyperlipidemia, diabetes, diabetic complications, irritable bowel syndrome, gastric ulcer, and gastritis.
机译:本发明涉及用于预防或治疗免疫疾病和代谢疾病的包含瑞巴派特前体的口服药物组合物。具体而言,本发明涉及能够预防或治疗诸如类风湿性关节炎和骨关节炎的免疫疾病以及诸如肥胖,高脂血症,糖尿病,糖尿病并发症,肠易激综合征,胃溃疡和胃炎的代谢疾病的口服药物组合物,通过包含瑞巴派特前体或其药学上可接受的盐作为活性成分。通过包含瑞巴派特前体或其药学上可接受的盐作为活性成分,根据本发明的口服药物组合物可具有与瑞巴派特相当或优于瑞巴派特的免疫疾病例如类风湿性关节炎和骨关节炎的治疗效果,并且代谢性疾病,例如肥胖,高脂血症,糖尿病,糖尿病并发症,肠易激综合症,胃溃疡和胃炎。

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