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Complex formulation comprising clopidogrel and asprin

机译:包含氯吡格雷和阿司匹林的复杂配方

摘要

The present invention relates to a complex formulation comprising clopidogrel and aspirin and a manufacturing method thereof. Stability is maintained even during storage and distribution, and the speed of disintegration of clopidogrel tablets is fast. The complex formulation comprises: a clopidogrel tablet including clopidogrel, an isomer thereof, or a pharmaceutically acceptable salt thereof; and an aspirin-containing particle which includes an aspirin core having aspirin, an isomer thereof, or a pharmaceutically acceptable salt thereof, and includes an enteric coating layer covering the core.
机译:本发明涉及包含氯吡格雷和阿司匹林的复合制剂及其制造方法。即使在储存和分配过程中也能保持稳定性,并且氯吡格雷片剂的崩解速度很快。该复合制剂包括:氯吡格雷片剂,其包括氯吡格雷,其异构体或其药学上可接受的盐;和含阿司匹林的颗粒,其包含具有阿司匹林,其异构体或其药学上可接受的盐的阿司匹林芯,并包括覆盖该芯的肠溶衣层。

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