BENZENESULFONAMIDE DERIVATIVES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR TREATING CANCER OR ASTHMA COMPRISING BENZENESULFONAMIDE DERIVATIVES AS ACTIVE INGREDIENTS

摘要

The present invention relates to a pharmaceutical composition for treating cancer or asthma comprising benzenesulfonamide derivatives represented by chemical formula 1 as active ingredients. According to the present invention, compounds represented by chemical formula 1, optical isomers thereof or pharmaceutically allowable salts thereof are effective in inhibiting not only activity of Pin1 isomerase but cell proliferation of cancer cell lines, thereby being usefully used as a pharmaceutical composition for preventing or treating cancer or chronic inflammation disease (asthma or the like).;COPYRIGHT KIPO 2017