首页> 外国专利> BENZENESULFONAMIDE DERIVATIVES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR TREATING CANCER OR ASTHMA COMPRISING BENZENESULFONAMIDE DERIVATIVES AS ACTIVE INGREDIENTS

BENZENESULFONAMIDE DERIVATIVES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR TREATING CANCER OR ASTHMA COMPRISING BENZENESULFONAMIDE DERIVATIVES AS ACTIVE INGREDIENTS

机译:苯并磺酰胺衍生物,其制备方法和药物组合物,用于治疗包含苯并磺酰胺衍生物作为活性成分的癌症或哮喘

摘要

The present invention relates to a pharmaceutical composition for treating cancer or asthma comprising benzenesulfonamide derivatives represented by chemical formula 1 as active ingredients. According to the present invention, compounds represented by chemical formula 1, optical isomers thereof or pharmaceutically allowable salts thereof are effective in inhibiting not only activity of Pin1 isomerase but cell proliferation of cancer cell lines, thereby being usefully used as a pharmaceutical composition for preventing or treating cancer or chronic inflammation disease (asthma or the like).;COPYRIGHT KIPO 2017
机译:本发明涉及用于治疗癌症或哮喘的药物组合物,其包含由化学式1表示的苯磺酰胺衍生物作为活性成分。根据本发明,由化学式1,其光学异构体或其药学上允许的盐表示的化合物不仅有效抑制Pin1异构酶的活性,而且还抑制癌细胞系的细胞增殖,因此有效地用作预防或预防癌症的药物组合物。治疗癌症或慢性炎症性疾病(哮喘等).; COPYRIGHT KIPO 2017

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