首页> 外国专利> ERLOTINIB NANOPARTICLE, MANUFACTURING METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING ERLOTINIB NANOPARTICLE

ERLOTINIB NANOPARTICLE, MANUFACTURING METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING ERLOTINIB NANOPARTICLE

机译:厄洛替尼纳米颗粒,其制造方法以及包含厄洛替尼纳米颗粒的药物组合物

摘要

The present invention relates to an erlotinib nanoparticle, a manufacturing method thereof, and a pharmaceutical composition containing the erlotinib nanoparticle, capable of making a patient more conveniently take a medicine by reducing a deviation between moments before and after a meal with an increase in the bioavailability of the medicine. The erlotinib nanoparticle is a solid dispersing body, made by dispersing an erlotinib free base in a diluting agent, and has D90 which is not more than 1000 nm. The diluting agent is selected from among a biocompatible polymer, a surfactant, saccharide, and a combination of the ingredients. The saccharide is selected from among a monosaccharide compound, a disaccharide compound, a polysaccharide compound, sugar-alcohol, and a combination of the ingredients.;COPYRIGHT KIPO 2017
机译:厄洛替尼纳米颗粒,其制造方法和包含厄洛替尼纳米颗粒的药物组合物,其能够通过减少进餐前后饭后之间的偏差而使患者更方便地服药,从而提高了生物利用度。药。厄洛替尼纳米颗粒是通过将厄洛替尼游离碱分散在稀释剂中而制成的固体分散体,并且D 90不大于1000nm。稀释剂选自生物相容性聚合物,表面活性剂,糖和成分的组合。糖类选自单糖化合物,二糖化合物,多糖化合物,糖醇及其成分的组合。; COPYRIGHT KIPO 2017

著录项

  • 公开/公告号KR20170110285A

    专利类型

  • 公开/公告日2017-10-11

    原文格式PDF

  • 申请/专利权人 BIO-SYNECTICS INC.;

    申请/专利号KR20160034450

  • 申请日2016-03-23

  • 分类号A61K9/14;A61K31/517;A61K9/20;A61K9/48;

  • 国家 KR

  • 入库时间 2022-08-21 13:26:31

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