pH- Drug Delivery System using Dual ionic pH-sensitive copolymer for Ischemic Brain Disease

摘要

The present invention relates to a drug delivery vehicle for the treatment of ischemic brain diseases comprising a dual ion pH-sensitive copolymer and SDF-1. The present invention also relates to a pharmaceutical composition for treating ischemic brain diseases comprising the drug delivery system. When a dual ion pH-sensitive copolymer containing SDF-1 as a nerve regeneration and protection factor according to the present invention is applied to a patient suffering from ischemic stroke as a drug delivery vehicle, it is possible to induce effective delivery of the therapeutic factor to a local lesion site And can be used effectively as a new therapeutic agent for ischemic brain diseases since it can offset the risk factors for side effects.