HDAC1 AcH3K14 AcH3K27 NANOG Method for Screening Therapeutic Agents against NANOG-mediated Cancer Using HDAC1 and AcH3K14 or AcH3K27 as biomarkers

摘要

The present invention relates to a screening method and a diagnostic composition for treating a NANOG-dependent endometriosis cancer, and more particularly, to a method for screening a therapeutic agent by diagnosing a NANOG-dependent or anti-cancer immunostaining cancer by targeting the HDAC1-AcH3K14 / AcH3K27 molecular axis. The screening method and the composition for diagnosing an anticancer agent or an anticancer immuno-tolerant cancer using the molecular axis of the new NANOG-HDAC1-AcH3K14 / AcH3K27 molecule as a pathological marker according to the present invention are more accurate than the anticancer agent or immunotherapy- And is very useful for rapid diagnosis and development of therapeutic agents.