首页> 外国专利> Fibroin Heavy chain Core Promoter of Bombyx mori and the Vector Thereof

Fibroin Heavy chain Core Promoter of Bombyx mori and the Vector Thereof

机译:家蚕丝素蛋白重链核心启动子及其载体

摘要

The present invention relates to a high expression promoter of a fibroin heavy chain gene of silkworm, a recombinant vector containing the promoter, and a method for producing silk-specific foreign protein using the same. The core promoter derived from the fibroin heavy chain gene according to the present invention and the high expression vector containing the fibroin heavy chain gene according to the present invention have a small size and high transformation efficiency and can induce high expression in the silkworm or silkworm body than the conventional BmA3 promoter, It is very useful industrially because of the improvement of the productivity of the heterologous protein and the convenience of the purification process.
机译:蚕丝蛋白重链基因的高表达启动子技术领域本发明涉及家蚕的丝蛋白重链基因的高表达启动子,含有该启动子的重组载体以及使用其的丝特异性外源蛋白的制备方法。源自本发明的纤维蛋白重链基因的核心启动子和含有本发明的纤维蛋白重链基因的高表达载体,体积小,转化效率高,可在蚕或蚕体内诱导高表达。与常规的BmA3启动子相比,由于异源蛋白的生产率提高和纯化工艺的便利,在工业上非常有用。

著录项

  • 公开/公告号KR101694829B1

    专利类型

  • 公开/公告日2017-01-11

    原文格式PDF

  • 申请/专利权人 대한민국;

    申请/专利号KR20140077248

  • 申请日2014-06-24

  • 分类号C12N15/10;A01K67/033;C12N15/86;

  • 国家 KR

  • 入库时间 2022-08-21 13:26:13

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