Virus Producing Cell Lines Having Increased Longevity and Method for Preparing the Same

摘要

The present invention relates to a mutant cell line inhibiting apoptosis and a method for preparing the same, and more particularly, to a cell line capable of inhibiting the signal transduction system involved in apoptosis by losing the function of Bst-2 (Tetherin) Thereby increasing the ability to produce virus. When the virus production mutant cell line produced by the present invention is used, the yield of virus production can be increased, which is useful for the prevention and treatment of viral diseases.