DNA VZV T DNA VACCINE COMPOSITION FOR PREVENTING AND TREATING HERPES ZOSTER AND METHOD OF ACTIVATING T-CELL TO VZV ANTIZEN BY USING THE SAME

摘要

The present invention provides a DNA vaccine composition for preventing and treating herpes zoster comprising at least one kind of plasmid including an insertion site of a VZV derived gene encoding a herpes zoster virus (VZV) protein, and other pharmaceutically acceptable components . The plasmid includes a plurality of plasmids containing different heterologous gene insertion sites. The plasmid contains a first plasmid comprising the insertion site of the first gene encoding the IE-62 protein (SEQ ID No. 1), a first plasmid containing the insertion site of the second gene encoding the IE-63 protein (SEQ ID No. 2) 2 plasmid and a third plasmid containing the insertion site of a third gene encoding the gE protein (SEQ ID NO: 3).