A MICROFLUIDIC DEVICE FOR CAPABLE OF SCREENING IMPROVED STRAINS WITH HIGH CARBON DIOXIDE FIXATION EFFICIENCY AND GROWTH RATE BASED ON CHEMOTAXIS BEHAVIOR AND A METHOD FOR SCREENING IMPROVED STRAINS WITH HIGH CARBON DIOXIDE FIXATION EFFICIENCY AND GROWTH RATE BASED ON CHEMOTAXIS BEHAVIOR USING THEREOF

摘要

A microfluidic device capable of selecting a strain having excellent carbon dioxide fixing efficiency and growth ability by using chemotaxis, and a method of selecting a strain having excellent carbon dioxide fixing efficiency and growth ability using chemotaxis. A microfluidic device capable of selecting a strain having excellent carbon dioxide fixing efficiency and growth ability by using chemotaxis according to an embodiment of the present invention includes a main channel; A medium and a cell inlet connected to one end of the main channel and having a first channel in which the organic carbon source is removed, a second channel in which bicarbonate ions are dissolved and a suspension containing cells are respectively introduced into the main channel; And a cell outlet connected to the other end of the main channel and through which the first medium, the second medium and the suspension are discharged, and the cell outlet, which are moved along the longitudinal direction of the main channel. The first medium, the second medium, And a concentration gradient of bicarbonate ions is formed along the width direction of the main channel in a region adjacent to the culture medium and the cell outflow portion of the main channel.;