Pharmaceutical composition comprising aralia elata extract fraction thereof or compounds isolated therefrom for preventing or treating erectile dysfunction

摘要

The present invention relates to a pharmaceutical composition for preventing or treating erectile dysfunction and a health functional food containing the Araliaceae Extract, a fraction thereof or a compound isolated therefrom as an active ingredient. The Araliae Extract of the present invention and the triterpenoid saponin compound isolated therefrom are excellent as a pharmaceutical composition and a health functional food for improving erectile dysfunction because of their excellent relaxation effect on penile cavernosal smooth muscle and promotion of penile erection . In addition, the Araliaceae according to the present invention are safe natural plant resources which have traditionally been used for edible purposes, and little side effects have been found in the acute and chronic toxicity tests using mice and rats. Thus, conventional PDE-5 inhibitors It can be used effectively as a safe erectile dysfunction improving agent without concern about toxicity.;