Th1- Th17- Th2- Composition for Preventing Improving or Treating of Th1-mediated Immune Disease Th17-mediated Immune Disease or Th2-mediated Immune Disease Comprising Extracts from Lactobacillus pentosus as an Active Ingredients

摘要

The present invention relates to Lactobacillus pentosusLactobacillusPentosus) KF340 strain (Accession No. KCCM 11675P) and a composition for preventing, ameliorating, or treating a Th1-mediated immune disease, a Th17-mediated immune disease, or a Th2-mediated immune disease comprising the strain as an active ingredient. The novel Lactobacillus pentosus KF340 strain according to the present invention is useful for the regulation of the ratio of immune tolerant cytokine (IL-10; anti-inflammatory cytokine) to regulatory T cells and regulatory B cell induction, immunologically active cytokine (IL-12) , Suppression of the production of immunoglobulin E (IgE), suppression of the production of Th1-related cytokines, Th17-related cytokines, and Th2-related cytokines in immunosuppressive reactions, and enhancement of allergic and inflammatory responses by IgA secretion It is expected that the compounds of the present invention may be usefully used as a composition for preventing, ameliorating or treating a Th1-mediated immune disease, a Th17-mediated immune disease, or a Th2-mediated immune disease, more preferably an allergic or inflammatory disease.;