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SOLID ORAL COMPOSITION CONTAINING DYES FOR USE IN ENDOSCOPIC DIAGNOSTICS
SOLID ORAL COMPOSITION CONTAINING DYES FOR USE IN ENDOSCOPIC DIAGNOSTICS
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机译:含染料的固体口腔组合物,用于内镜诊断
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摘要
1. A solid composition containing at least one dye in combination with at least one physiologically acceptable excipient, which contains: a) a matrix that contains lipophilic compounds with a melting point below 90 ° C, and optionally amphiphilic compounds in which at least at least partially indicated at least one dye, b) an external matrix that contains hydrophilic compounds in which the lipophilic matrix and optionally amphiphilic matrix are dispersed; c) optionally other physiological acceptable excipients; d) optional gastro-resistant coating for use in endoscopic diagnostics, characterized in that more than two of its standard dosages are orally administered to a person according to the fractionated regimen in which the total amount is from 50 to 500 mg, preferably from 100 to 400 mg, indicated by at least one dye is administered to the indicated person 48 hours before endoscopic diagnosis. 2. A solid composition according to claim 1, wherein the total dose is fractionated into more than two standard dosages containing the same amount of dye, which is considered the active ingredient. A solid composition according to claim 1, wherein the dosage units are four, six, eight or a plurality of unit dosages. A solid composition for use according to claim 1, wherein said at least one dye is selected from methylene blue, Congo red, indigo carmine, toluidine blue, or mixtures thereof. A solid composition for use according to claim 4, wherein said at least one dye is methylene blue. A solid composition for use according to claim 4, wherein
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