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ASSESSMENT OF ACTIVITY OF CELLULAR SIGNALING WAYS USING LINEAR COMBINATION (S) OF TARGET GENE EXPRESSIONS

机译:使用靶基因表达的线性组合评估细胞信号传递途径的活性

摘要

The present application mainly relates to specific methods for inferring activity of a cellular signaling pathway in tissue and/or cells of a medical subject based at least on expression levels of one or more target gene(s) of the cellular signaling pathway measured in an extracted sample of the tissue and/or cells of the medical subject, an apparatus comprising a digital compressor configured to perform such methods and a non-transitory storage medium storing instructions that are executable by a digital processing device to perform such methods.
机译:本申请主要涉及至少基于在提取物中测量的细胞信号传导途径的一个或多个靶基因的表达水平来推断医学对象的组织和/或细胞中细胞信号传导途径的活性的具体方法。样本,医学对象的组织和/或细胞的样本,包括被配置为执行这样的方法的数字压缩器和存储由数字处理设备可执行以执行这样的方法的指令的非暂时性存储介质的设备。

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