METHOD OF PRODUCING NANOCAPSULES OF ROSUVASTATIN IN CARRAGEENAN

摘要

FIELD: nanotechnology.;SUBSTANCE: invention relates to a method of producing nanocapsules of rosuvastatin, characterised by that rosuvastatin is slowly added to a suspension of carrageenan in hexane, in presence of 0.005 g of an E472c preparation with mixing at 1,000 rpm, with weight ratio shell: nucleus 3:1 or 1:5, then adding 5 ml of 1,2-dichloroethane; prepared suspension is filtered and dried at room temperature.;EFFECT: invention provides a simpler and faster process of producing nanocapsules, reduces loss during production (higher weight yield).;1 cl, 3 ex, 1 dwg