RADIX SALVIAE MILTIORRHIZAE (DAN SHEN) OR PREPARATIONS THEREOF APPLICATION FOR PREPARATION OF DRUGS FOR TREATMENT OF DISEASES RELATED TO LIVER FIBROSIS

摘要

FIELD: pharmacology.;SUBSTANCE: medicinal product intended for treatment of diseases associated with liver fibrosis contains an aqueous salvia miltiorrhiza bunge root (Radix Salviae Miltiorrhizae) extract, obtained by pouring water 7 times the weight of the root, and boiling of the resulting mixture 2 times for 2 hours. After the decoctions combination, the solution is filtered and concentrated, the extract supernatant is centrifuged and passed through macroporous resin. The resin is then washed with water, eluted with ethanol, and the resulting solution is concentrated to obtain a Radix Salviae Miltiorrhizae root extract.;EFFECT: agent is effective for treatment of diseases associated with liver fibrosis, inhibits high α-RSM expression.;9 cl, 3 dwg, 5 tbl, 5 ex