SILICON-ZINC-BORON-CONTAINING GLYCEROGYDROGEL FOR LOCAL APPLICATION, FACILITATING FOR VULNERARY, REGENERATIVE, BACTERICIDAL AND ANTIFUNGAL ACTIVITY

摘要

FIELD: pharmacology.;SUBSTANCE: invention is a silicon-zinc-boron-containing glycerogyrogel for topical application, with wound-healing, regenerative, bactericidal and antifungal activity, with composition corresponding to the formulamSi(C₃H₇O₃)₄⋅ZnC₃H₆O₃⋅nHB(C₃H₆O₃)₂⋅xC₃H₈O₃⋅yH₂O, where1≤m≤3, 1≤n≤2, 9≤x≤15, 28≤y≤70, obtained by interaction of silicon tetraglycerolate in an excess of glycerin Si(C₃H₇O₃)₄⋅xC₃H₈O₃, where 1.5≤x≤4.5, zinc monoglycerolate in excess of glycerin⋅ ZnC₃H₆O₃⋅6C₃H₈O₃, boron bisglycerolate HB(C₃H₆O₃)₂ and water in a molar ratio of Si(C₃H₇O₃)₄:ZnC₃H₆O₃:HB(C₃H₆O₃)₂:C₃H₈O₃:H₂O, equal to (1÷3):1:(1÷2):(9÷15):(28÷70), at a temperature of 40-60°C and stirring.;EFFECT: creation of a product that is safe to use and has a wide range of pharmacological activities - wound healing, regenerating, bactericidal and fungistatic, in a convenient form for topical application, storage stable, well reproducible in the production process using available raw materials.;2 tbl, 5 ex